This chapter explores critically ethical concerns arising from forms of suffering to which domesticated nonhuman animals are subjected in scientific instruction and research and within the industrial-factory-farm-food complex, as well as other contexts. Consideration is given to the views of Arthur Schopenhauer on suffering, René Descartes’s designation of ontological differences between human and non-human animals, and Donna Haraway’s reconfiguration of the relationship between human and nonhuman animals in scientific laboratory settings. Proceeding from a discussion of David Benatar’s “antinatalist” views (...) the focus of analysis is on the forms of suffering imposed on domesticated nonhuman animals by humans. In response to ethical concerns raised about the suffering inflicted on nonhuman animals in the course of scientific research, scientists have sought a “solution” in the form of genetically engineered nonhuman animals whose responses to painful stimuli are presented as modulated to reduce pain. This reductive conceptualization of suffering reduces the complexity of suffering to physical sensation alone and does not engage with the ethical issues involved. Drawing on the work of Emmanuel Levinas and Albert Schweitzer the chapter concludes that an ethical solution to the complex issues explored lies in refraining from exposing nonhuman animals to pain and suffering. (shrink)

We give an examination of the automorphism group Aut of a countable recursively saturated model M of PA. The main result is a characterisation of strong elementary initial segments of M as the initial segments consisting of fixed points of automorphisms of M. As a corollary we prove that, for any consistent completion T of PA, there are recursively saturated countable models M1, M2 of T, such that Aut[ncong]Aut, as topological groups with a natural topology. Other results include a classification (...) of the normal subgroups of Aut of the form [lcub]g: g [uharr] A = idA[rcub], for sets A M, and a highly homogeneous representation of Aut as a subgroup of Aut. (shrink)

Background Randomized controlled trials are central to generating knowledge about effectiveness of interventions as well as risk, protective and prognostic factors related to diseases in emergency newborn care. Whether prospective participants understand the purpose of research, and what they perceive as the influence of the context on their understanding of the informed consent process for RCTs in emergency obstetric and newborn care are not well documented. Methods Conceptual review. Discussion Research is necessary to identify how the illnesses may be prevented, (...) to explore the causes, and to investigate what medications could be used to manage such illness. Voluntary informed consent requires that prospective participants understand the disclose information about the research, and use this to make autonomous informed decision about participation, in line with their preferences and values. Yet the emergency context affects how information may be disclosed to prospective research participants, how much participants may comprehend, and how participants may express their voluntary decision to participate, all of which pose a threat to the validity of the informed consent. I challenge the claim that the ‘understanding’ of research is always necessary for ethical informed consent for research during emergency care. I argue for reconceptualization of the value of understanding, through recognition of other values that may be equally important. I then present a reflective perspective that frames moral reflection about autonomy, beneficence and justice in research in emergency research. Conclusion While participant ‘understanding’ of research is important, it is neither necessary nor sufficient for a valid informed consent, and may compete with other values with which it needs to be considered. (shrink)

This book is a groundbreaking history of balance, exploring how a new model of equilibrium emerged during the medieval period.

Let M be a countable recursively saturated model of Th(), and let GAut(M), considered as a topological group. We examine connections between initial segments of M and subgroups of G. In particular, for each of the following classes of subgroups HG, we give characterizations of the class of terms of the topological group structure of H as a subgroup of G. (a) for some (b) for some (c) for some (d) for some (Here, M(a) denotes the smallest M containing a, (...) , , and .). (shrink)

This undergraduate textbook covers the key material for a typical first course in logic, in particular presenting a full mathematical account of the most important result in logic, the Completeness Theorem for first-order logic. Looking at a series of interesting systems, increasing in complexity, then proving and discussing the Completeness Theorem for each, the author ensures that the number of new concepts to be absorbed at each stage is manageable, whilst providing lively mathematical applications throughout. Unfamiliar terminology is kept to (...) a minimum, no background in formal set-theory is required, and the book contains proofs of all the required set theoretical results. The reader is taken on a journey starting with König's Lemma, and progressing via order relations, Zorn's Lemma, Boolean algebras, and propositional logic, to completeness and compactness of first-order logic. As applications of the work on first-order logic, two final chapters provide introductions to model theory and nonstandard analysis. (shrink)

Biobanks are proliferating rapidly worldwide because they are powerful tools and organisational structures for undertaking medical research. By linking samples to data on the health of individuals, it is anticipated that biobanks will be used to explore the relationship between genes, environment and lifestyle for many diseases, as well as the potential of individually-tailored drug treatments based on genetic predisposition. However, they also raise considerable challenges for existing legal frameworks and research governance structures. This book critically examines the current governance (...) structures in place for biobanks in England and Wales. It shows that the technologies, techniques and practices involved in biobanking do not always conform neatly to existing legal principles and frameworks that apply to other areas of medical research. Using a socio-legal approach, including interview data gathered from the scientific community, this book provides unique insights and makes recommendations about appropriate governance mechanisms for biobanking in the future. It also explores the issues around the secondary use of information, such as consent and how to protect privacy, when biobanks are accessed by a number of different third parties. These issues have relevance both within England and Wales and to a wide international audience, as well as for other areas where large datasets are used.--Back cover. (shrink)

The use of genome-wide association studies in medical research and the increased ability to share data give a new twist to some of the perennial ethical issues associated with genomic research. GWAS create particular challenges because they produce fine, detailed, genotype information at high resolution, and the results of more focused studies can potentially be used to determine genetic variation for a wide range of conditions and traits. The information from a GWA scan is derived from DNA that is a (...) powerful personal identifier, and can provide information not just on the individual, but also on the individual's relatives, related groups, and populations. Furthermore, it creates large amounts of individual-specific digital information that is easy to share across international borders. This paper provides an overview of some of the key ethical issues around GWAS: consent, feedback of results, privacy, and the governance of research. Many of the questions that lie ahead of us in terms of the next generation sequencing methods will have been foreshadowed by GWAS and the debates around ethical and policy issues that these have created. (shrink)

We generalize Specker's theorem on typical ambiguity, that NF and TST + Ambiguity have the same stratified consequences, to the subschemes Amb(Γ) of ambiguity restricted to classes of sentences Γ with certain natural closure conditions.

Counterfactualism is a useful process for historians as a thought-experiment because it offers grounds to challenge an unfortunate contemporary historical mindset of assumed, deterministic certainty. This article suggests that the methodological value of counterfactualism may be understood in terms of the three categories of common ahistorical errors that it may help to prevent: the assumptions of indispensability, causality, and inevitability. To support this claim, I survey a series of key counterfactual works and reflections on counterfactualism, arguing that the practice of (...) counterfactualism evolved as both cause and product of an evolving popular assumption of the plasticity of history and the importance of human agency within it. For these reasons, counterfactualism is of particular importance both historically and politically. I conclude that it is time for a methodological re-assessment of the uses of such thought-experiments in history, particularly in light of counterfactualism's developmental relatedness to cultural, technological, and analytical modernity. (shrink)

In the 1950s and 1960s Freudian theory was deemed to be a vital part of the sociological tradition, but since then it has fallen from favor, largely because of the simplifications and misinterpretations both by Freud's sociological critics and by his supporters. Chief among such misunderstandings is the tendency to view Freud's social theory as a variant of that of Hobbes, in which a selfish and asocial human nature is made social through the imposition of external constraints; these constraints, as (...) Durkheim stated, eventually are "internalized" into the personalities of social beings. Against such a claim this paper argues that Freud's views differ profoundly from those of Hobbes and that the myth of the Hobbesian Freud has so distorted Freud's most fundamental concepts that their social theoretical significance has been largely obscured. (shrink)

There is an urgent need to learn how to appropriately integrate technologies into dementia care. The aims of this Delphi study were to project which technologies will be most prevalent in dementia care in five years, articulate potential benefits and risks, and identify specific options to mitigate risks. Participants were also asked to identify technologies that are most likely to cause value tensions and thus most warrant a conversation with an older person with mild dementia when families are deciding about (...) their use. Twenty-one interdisciplinary domain experts from academia and industry in aging and technology in the U.S. and Canada participated in a two-round online survey using the Delphi approach with an 84% response rate and no attrition between rounds. Rankings were analyzed using frequency counts and written-in responses were thematically analyzed. Twelve technology categories were identified along with a detailed list of risks and benefits for each. Suggestions to mitigate the most commonly raised risks are categorized as follows: intervene during design, make specific technical choices, build in choice and control, require data transparency, place restrictions on data use and ensure security, enable informed consent, and proactively educate users. This study provides information that is needed to navigate person-centered technology use in dementia care. The specific recommendations participants offered are relevant to designers, clinicians, researchers, ethicists, and policy makers and require proactive engagement from design through implementation. (shrink)

An introduction to 25 major philosophers for kids ages 8 to 12. Learning about philosophy encourages kids to ponder big ideas and ask deep questions about the world around them. This book introduces kids to 25 major Eastern and Western philosophers with easy-to-understand explanations of their most well-known ideas. What sets this book about philosophy for kids apart: An introduction to philosophy--Kids will learn more about what a philosopher is, what kind of questions they ask, and the history of Eastern (...) and Western philosophy. Thinkers throughout time--This book covers ancient philosophers like Socrates and Confucius, medieval philosophers like Averroes and Hildegard of Bingen, and modern philosophers like Simone de Beauvoir and Mohandas Gandhi. Thought-provoking questions--Get kids thinking with philosophical questions that help them consider opposing ideas, develop strong arguments, and strengthen their communication skills. Pick up this kid-friendly choice in philosophy books and inspire the budding philosopher in your life. (shrink)

Many philosophers embrace both evolution and existentialism as though these two views provide a mutually supportive foundation for atheism. The story goes that evolution tells us life is meaningless while existentialism tells us what to do about it. In this paper, I aim to debunk this story. I begin by explaining the existentialist quest for the meaning of life. Then I explain why it is inconsistent with the principles of evolution. In the end, I argue that the quest for the (...) meaning of life should be abandoned. It is a misleading project that science renders unnecessary. Looked at in this light, existentialism appears as a stripped down version of religion, vainly clinging to dramatic fantasies about human life. Evolution has had a deep and valuable impact upon philosophy. It will not have completed its work, however, until it stamps out existentialism and its atavistic angst once and for all. (shrink)

This book develops and defends a new understanding of Kant's account of perceptual representation, showing that it underlies the main doctrines of the Critique of Pure Reason. Intuitions consist of formal unifications by the schematized categories that projectively represent both time and external objects and enable synthetic a priori knowledge.

Disillusioned with college, Everett takes a position teaching philosophy to kids at an innovative summer enrichment academy on an island off the New England coast. The academy is run by fellow student Juniper’s Aunt Laura, and at Laura’s recommendation, Everett uses as his curriculum an exploration of the concept of happiness as described by ten of history’s most significant philosophers. This idea is sparked by a collection of readings saved by Laura’s grandmother, a teacher who originally owned the mansion in (...) which the academy is housed. But along with those readings is a set of clues that lead to a rare historic work by an ancient Greek philosopher—a codex—that is hidden in the mansion. So Everett sets to work preparing the readings for his students while simultaneously solving the clues with Juniper to find the codex. -/- What Everett doesn’t know, however, is that he and Juniper are not the only ones on the hunt for the codex, and the stakes are high. The book is extremely valuable, and there are plenty of people who would like to get their hands on the money it would bring at auction, including the people who are funding Laura’s academy. The question of rightful ownership and the mystery of the codex’s location deepen as Everett and Juniper solve the riddles to find the keys that will open whatever safe contains the ancient text. And all the while, Everett finds himself falling for Juniper. -/- He’s also working through the collection of philosophical readings about happiness, taking each one in turn and presenting it in clear, concise, modern English to his students, who are eager to discover how to lead a happy life. Everett is equally eager to make the same discovery, and he carefully considers each philosopher’s thinking on the matter, applying the concepts to his own life in an effort to understand them in the context of a young person in the real world struggling to figure out what he wants to do with his future. -/- As Everett gains clarity on what he wants out of life, however, the mystery of the codex takes a dark turn, and everything he thought he knew is turned upside down. Who will end up with the codex? What will happen to the academy? And will Everett be able to take everything that he has learned—both the good and the bad—to build a life for himself that will bring him the most happiness? -/- There is an accompanying guidebook for this novel. (shrink)

The Onion, with its unique brand of deadpan satirical humor, has become a familiar part of the American scene. The newspaper has a readership of over a million, and it reaches millions more with its spin-off books and The Onion News Network. The Onion has shown us that standard ways of thinking about the news have their grotesque and silly side, and this invites philosophical examination. Twenty-one philosophers were commissioned to figure out just what makes the Onion so truthful and (...) insightful. Are the Onion writers truly cynical, or just cynically faking it? Does the Onion really have a serious point of view on religion? On sex? On politics? Who cares what Area Man thinks? If everyone’s so dumb, how come so many Onion readers keep on laughing at how dumb they are? (shrink)

Embedded pragmatic clinical trials (PCTs), like other types of randomized comparative-effectiveness research (CER) studies, are sometimes conducted without informed consent. Indeed, authors of both...

Fodor and others who think that scientific, computational psychology will vindicate commonsense belief-desire psychology have maintained that belief can be identified with the explicit storage of a token with appropriate content. I review and develop problems for the explicit storage view and show that a more plausible account identifies belief with the disposition to use a token with appropriate content in explicit reasoning and planning processes and as a basis for action. I argue that this type of inner disposition account (...) will also apply to most other common sense attitudes. The result is a realism about commonsense belief-desire psychology that is more modest than Fodor's: While such inner dispositions probably do exist, these states will probably not be the main focus of scientific psychological theories. (shrink)

We present some general results concerning the topological space of cuts of a countable model of arithmetic given by a particular indicator Y.The notion of “indicator” is de.ned in a novel way, without initially specifying what property is indicated and is used to de.ne a topological space of cuts of the model. Various familiar properties of cuts are investigated in this sense, and several results are given stating whether or not the set of cuts having the property is comeagre.A new (...) notion of “generic cut” is introduced and investigated and it is shown in the case of countable arithmetically saturated models M ⊧ PA that generic cuts exist, indeed the set of generic cuts is comeagre in the sense of Baire, and furthermore that two generic cuts within the same “small interval” of the model are conjugate by an automorphism of the model.The paper concludes by outlining some applications to constructions of cuts satisfying properties incompatible with genericity, and discussing in model-theoretic terms those properties for which there is an indicator Y. (shrink)

Book reviewed in this article: Mama Might Be Better Off Dead: The Failure of Health Care in Urban America. By Laurie Kaye Abraham. Not All of Us Are Saints: A Doctor's Journey with the Poor. By David Hilfiker.

The United Kingdom is a leader in genomics research, and the presence of numerous types of biobanks and the linking of health data and research within the UK evidences the importance of biobank-based research in the UK. There is no biobank-specific law in the UK and research on biobank materials is governed by a confusing set of statutory law, common law, regulations, and guidance documents. Several layers of applicable law, from European to local, further complicate an understanding of privacy protections. (...) Finally, biobanks frequently contain data in addition to the samples; the legal framework in the UK generally differentiates between data and samples and the form of the data affects the applicability of legal provisions. Biobanks must be licensed by the Human Tissue Authority; certain projects must be reviewed by Research Ethics Committees, and all projects are encouraged to be reviewed by them. Data Access Committees in biobanks are also common in the UK. While this confusing array of legal provisions leaves privacy protections in biobanking somewhat unclear, changes at the EU level may contribute to harmonization of approaches to privacy. (shrink)

Let= {0,1, +,·,<} be the usual first-order language of arithmetic. We show that Peano arithmetic is the least first-order-theory containingIΔ0+ exp such that every complete extensionTof it has a countable modelKsatisfying(i)Khas no proper elementary substructures, and(ii) wheneverL≻Kis a countable elementary extension there isandsuch that.Other model-theoretic conditions similar to (i) and (ii) are also discussed and shown to characterize Peano arithmetic.

Wikipedia is known as a free online encyclopedia. Wikipedia uses largely transparent writing and editing processes, which aim at providing the user with quality information through a democratic collaborative system. However, one aspect of these processes is not transparent—the identity of contributors, editors, and administrators. We argue that this particular lack of transparency jeopardizes the validity of the information being produced by Wikipedia. We analyze the social and ethical consequences of this lack of transparency in Wikipedia for all users, but (...) especially students; we assess the corporate social performance issues involved, and we propose courses of action to compensate for the potential problems. We show that Wikipedia has the appearance, but not the reality, of responsible, transparent information production. (shrink)